Post: Evidence suggests link between teen cannabis use and psychotic disorders may be stronger than previously thought

Credit: Liza Summer from Pexels A new study published in the journal Psychological Medicine estimates that teens using cannabis are at an 11-times higher risk of developing a psychotic disorder compared to teens not using cannabis. The paper is titled "Age-dependent association of cannabis use with risk of psychotic disorder."

This finding suggests that the association between cannabis and psychotic disorders may be stronger than indicated by previous research, which has relied largely on older data when cannabis was less potent than today. For context, the average THC potency of cannabis in Canada has increased from roughly 1% in 1980 to 20% in 2018.

Researchers from the University of Toronto, the Center for Addiction and Mental Health (CAMH), and ICES, linked recent population-based survey data from over 11,000 youth in Ontario, Canada, to health service use records including hospitalizations, emergency department (ED) visits, and outpatient visits.

The study is the first to show an age-dependent association between self-reported cannabis use and subsequent psychotic disorder diagnosis, which adds to a growing body of research on the mental health risks associated with cannabis.

"We found a very strong association between cannabis use and risk of psychotic disorder in adolescence. Surprisingly, we didn’t find evidence of association in young adulthood," says lead author André McDonald, who conducted the study at ICES as part of his Ph.D. at the University of Toronto. A new study shows that teens using cannabis are at 11 times higher risk of developing a psychotic disorder compared to teens not using cannabis. Credit: ICES McDonald is now a postdoctoral fellow at the Peter Boris Center for Addictions Research and the Michael G. DeGroote Center for Medicinal Cannabis Research at McMaster University. "These findings are consistent with the neurodevelopmental theory that teens are especially vulnerable to the effects of cannabis."

Of the teens who were hospitalized or visited an ED for a psychotic disorder, roughly five in six had previously reported cannabis use. McDonald points out that "the vast majority of teens who use cannabis will not develop a psychotic disorder, but according to these data, most teens who are diagnosed with a psychotic […]

Evidence suggests link between teen cannabis use and psychotic disorders may be stronger than previously thought