Cannabis interacts with the endocannabinoid system to regulate pain, mood, and inflammation. THC and CBD offer potential benefits for brain health, pain relief, and metabolic disorders. Cannabis is often hailed for its relaxing effects, but did you know it’s also linked to a complex system in our body called the endocannabinoid system (ECS)? The ECS plays a crucial role in regulating several physiological functions, from pain and inflammation to mood and memory. This system is composed of receptors located throughout the brain, immune system, and nervous system, all working together to maintain balance, or homeostasis , in the body.
When cannabinoids—like THC and CBD—are introduced into the body, they interact with two main types of receptors: CB1 and CB2. CB1 receptors are primarily found in the brain and central nervous system, while CB2 receptors are located in the immune system. THC, the compound most commonly associated with the “high” from cannabis, binds to CB1 receptors, triggering the psychoactive effects that many people associate with cannabis. On the other hand, CBD, which doesn’t produce a high, interacts with both CB1 and CB2 receptors, promoting therapeutic effects like reducing anxiety, managing pain, and alleviating inflammation. The Brain-Boosting Potential of THC
One of the most intriguing areas of cannabis research involves its potential effects on brain health. Recent studies suggest that THC might actually stimulate neurogenesis, the creation of new brain cells. This could have important implications for treating cognitive decline associated with aging and neurodegenerative diseases like Alzheimer’s. For example, THC’s interaction with CB1 receptors in the brain helps modulate neurotransmitter release, which may protect against or slow down conditions related to memory and learning.
A musician who has experienced the effects of THC in a personal way is Melissa Etheridge, who has openly shared her journey with cannabis, especially in the context of her breast cancer treatment. Etheridge credits cannabis with helping her cope with the pain and emotional toll of the disease, as well as enhancing her ability to focus during the creative process. The potential for cannabinoids to positively impact cognitive function, especially for individuals facing age-related or medical […]

Microdosing 101
Kate Schroeder LPC, LMHC, NCC Key points Microdosing should be