A lesser-known cannabinoid known as CBG has surprised scientists after a first-ever human clinical trial found that it appears to improve memory, while also “significantly” reducing anxiety and stress.
The non-intoxicating cannabinoid might not be as well-known as THC and CBD, for example, but as it’s grown in popularity, researchers at Washington State University (WSU) and the University of California at Los Angeles (UCLA) set out to investigate its therapeutic potential amid anecdotal, survey-based reports about its therapeutic potential.
The study, published in the journal Scientific Reports this month, found that cannabigerol, or CBG, caused a “significant overall reductions in anxiety as well as reductions in stress” among study participants compared to the placebo. “CBG also enhanced verbal memory relative to placebo,” with “no evidence of subjective drug effects or impairment.”
That finding about CBG’s effects on memory took the research team by surprise. Lead author and WSU associate professor of psychology Carrie Cuttler said in a press release that they “triple-checked to ensure accuracy, and the enhancement was statistically significant.” “Relative to placebo, there was a significant main effect of CBG on overall reductions in anxiety as well as reductions in stress… CBG also enhanced verbal memory relative to placebo.” “The finding that it significantly enhanced [memory] was kind of shocking to me and completely, entirely unexpected, which was why I triple-checked the direction and the result,” Cuttler told Marijuana Moment in a phone interview on Wednesday, adding that “we definitely want to replicate that finding before we make too big of a deal about it.” Cannabigerol #CBG had promising clinical trial results: reducing anxiety without the intoxication typically associated with whole plant #cannabis — #WSU -led study https://t.co/mfOmmm2qoS — WSU News (@WSUNews) July 31, 2024 To assess the efficacy of CBG, researchers conducted a double-blind, placebo-controlled field trial where 34 healthy adults were given either 20mg of hemp-derived CBG or a placebo tincture over two sessions.
Participants were first asked to complete online assessments rating their anxiety, stress and mood. After administering the cannabinoid, they took another series of assessments, including a survey, stress test and verbal memory test.
“CBG may represent […]
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