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Post: New Brain Stimulation Target Could Treat PTSD

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New Brain Stimulation Target Could Treat PTSD
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Summary: A new study suggests that neurostimulation targeting specific brain circuits may help treat PTSD in veterans. Researchers found that veterans with damage to brain areas connected to the amygdala, the brain’s fear center, were less likely to develop PTSD.

Using data from Vietnam War veterans with brain injuries, the team identified a brain circuit linked to PTSD, opening up potential treatment options with transcranial magnetic stimulation (TMS). Further research is needed to confirm its efficacy in broader populations.

Key Facts : Brain circuit damage linked to reduced PTSD risk in veterans.

TMS targeting this brain circuit showed positive effects in PTSD trials.

Future trials are needed for wider clinical use and FDA approval.

Source: Brigham and Women’s Hospital

A new study led by researchers at Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, suggests that using neurostimulation therapies on a specific brain network could treat post traumatic stress disorder (PTSD) in veterans.

By evaluating 193 participants in the Vietnam Head Injury Study with penetrating traumatic brain injury, the team found those with damage connected to their amygdala, the fear center of the brain, were less likely to develop PTSD.

Their results are published in Nature Neuroscience. The study suggests lesions that could protect against PTSD map to a specific brain circuit connected to the amygdala and the medial prefrontal cortex. Credit: Neuroscience News “This is a very real brain disease, and we can localize it to certain brain circuits,” said corresponding author Shan Siddiqi, MD, a psychiatrist in the Brigham’s Center for Brain Circuit Therapeutics and an assistant professor of Psychiatry at Harvard Medical School.“Unfortunately, people sometimes assume PTSD has to do with how mentally strong or weak a person is, but it has nothing to do with moral character.”Siddiqi collaborated with other researchers from the Brigham’s Center for Brain Circuit Therapeutics, as well as investigators from the Feinberg School of Medicine at Northwestern University, Brown University Alpert School of Medicine, and Duke University School of Medicine.He said previous studies have shown people with damage to the amygdala are less likely to get PTSD, but the […]

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