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Post: New deep learning model is ‘game changer’ for measuring embryo development

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New deep learning model is ‘game changer’ for measuring embryo development
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Pond snail embryos at the University of Plymouth Research led by the University of Plymouth has shown that a new deep learning AI model can identify what happens and when during embryonic development, from video.

Published today (Wednesday 29 May) in the Journal of Experimental Biology , the study highlights how the model, known as Dev-ResNet, can identify the occurrence of key functional developmental events in pond snails, including heart function, crawling, hatching and even death.

A key innovation in this study is the use of a 3D model that uses changes occurring between frames of the video, and enables the AI to learn from these features, as opposed to the more traditional use of still images.

The use of video means features ranging from the first heartbeat, or crawling behaviour, through to shell formation or hatching are reliably detected by Dev-ResNet, and has revealed sensitivities of different features to temperature not previously known.

While used in pond snail embryos for this study, the authors say the model has broad applicability across all species, and they provide comprehensive scripts and documentation for applying Dev-ResNet in different biological systems.

In future, the technique could be used to help accelerate understanding on how climate change, and other external factors, affect humans and animals.

The work was led by PhD candidate, Ziad Ibbini, who studied BSc Conservation Biology at the University, before taking a year out to upskill himself in software development, then beginning his PhD. He designed, trained and tested Dev-ResNet himself.

He said: “Delineating developmental events – or working out what happens when in an animal’s early development – is so challenging, but incredibly important as it helps us to understand changes in event timing between species and environments.

“Dev-ResNet is a small and efficient 3D convolutional neural network capable of detecting developmental events using videos, and can be trained relatively easily on consumer hardware.“The only real limitations are in creating the data to train the deep learning model – we know it works, you just need to give it the right training data.“We want to equip the wider scientific community with the tools that will enable them […]

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