Key Takeaways
> Dr. Corneliu Giurgea created the first racetam nootropic, Piracetam, discovering that it boosts cognitive abilities even in healthy people.
All racetams are synthetic compounds, sharing a similar chemical structure, and are used for various neurocognitive disorders.
Every racetam affects acetylcholine levels in your brain and needs to be taken with a quality choline supplement like Alpha GPC or CDP-Choline.
The seven most popular racetams are Piracetam, Aniracetam, Coluracetam, Nefiracetam, Oxiracetam, Phenylpiracetam, and Pramiracetam, each having specific benefits such as improved cognitive function, reduced anxiety, memory enhancement, increased blood flow, etc.
Each racetam has unique mechanisms of action, providing different benefits, hence, choosing the best one depends on your individual needs and requirements.
The very first racetam nootropic was created by Dr. Corneliu Giurgea at the Belgian-based pharmaceutical company UCB Pharma in the 1964.
Dr. Giurgea’s intention was to develop a calming-type drug for motion sickness. GABA is the calming neurotransmitter and Piracetam is a cyclic derivative of GABA .
But in spite of its connection with GABA , Piracetam didn’t show any behavior associated with this calming neurotransmitter. And cannot directly affect GABA receptors .Instead, Dr. Giurgea discovered that Piracetam was able to boost cognitive abilities even in healthy people. The company launched this new ‘drug’ as ‘Nootropil’ in Europe in the early 1970’s. How do racetams work? Dozens of racetam derivatives have since been developed based on the original Piracetam . All synthetic compounds, racetams share a pyrrolidone nucleus at their chemical structure core.Several of these racetams are now sold as prescription drugs in countries around the world. And are prescribed for dementia, Alzheimer’s disease, stroke recovery, ADHD , epilepsy and other neurocognitive disorders.In the USA, racetams are available OTC without a prescription. But oddly enough are not classified as “dietary supplements”. Instead, the racetams described below are offered for “research” purposes only.If you are new to the world of nootropics , and would like to try one of the racetams , but are not sure which one to choose, this post may help.Below is a brief description of the 7 most popular racetams in use […]

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