Two-Phase Study Leads to Monteloeder’s Newest Nootropic for Cognitive Performance Two-Phase Study Leads to Monteloeder’s Newest Nootropic for Cognitive Performance
PR Newswire
MADRID, Feb. 25, 2025
Mindrevive™, composed of extracts of sage and Japanese pagoda tree, found to help enhance mental resilience in older adults
MADRID, Feb. 25, 2025 /PRNewswire/ — A new study illustrates the research journey behind the creation of Monteloeder’s latest nootropic formulation Mindrevive™. The study spans the process from laboratory analysis of various botanical candidates to assess and compare their cognitive potential, to a clinical trial of the final selected composition. Sage extract ( Salvia officinalis ) together with Japanese pagoda tree ( Sophora japonica ) emerged as the combination with the highest cognitive support potential demonstrating significant improvements in memory, learning and execution in a clinical trial. The results of this two-in-one study led nutraceutical leader Monteloeder, a subsidiary of SUANNUTRA to create its proprietary "smart supplement" Mindrevive™, designed to help preserve cognitive vitality specifically in adults aged 50 and older who are going through typical age-related changes. Serving the healthy ageing category, the composition targets memory, mental clarity and focus.
Specifically, the compounds in Mindrevive™ were found to help: Reduce oxidative stress
Increase neuronal survival and regeneration
Activate antioxidant defenses
Enhance memory and learning Support growth factor release (NGF, BDNF, VEGF) Maintain cognitive health Study Details The two-phase study ushered in a research-driven approach to formulation. Led by Pau Navarro, PhD, published December 2024 in Applied Sciences first involved in vitro analysis of nine unique botanical compounds that were assessed for their nootropic properties. These included water-ethanol extracts of bilberry, blueberry, bacopa ( Bacopa monnieri ), sage, saffron, rhodiola ( Rhodiola rosea ), ginkgo biloba, panax ginseng roots, and gotu kola, and, Japanese pagoda tree. These herb extracts were tested in human neural stem cell cultures exposed to oxidative stress. The researchers analyzed each botanical’s ability to suppress harmful reactive oxygen and reactive nitrogen species (ROS and RNS), to promote cell survival, and to stimulate neural cell growth factors.Results of this first phase demonstrated that sage standardized in rosmarinic acid exhibited the most noticeable effects […]
Two-Phase Study Leads to Monteloeder’s Newest Nootropic for Cognitive Performance
