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Post: UB enters multinational partnership for cannabinoid research and development

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UB enters multinational partnership for cannabinoid research and development
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Health researchers working with DENT Neurologic Institute, Jamaica pharmaceutical company to increase global clinical research

By Laurie Kaiser

Release Date: February 20, 2025 Gene Morse "Although cannabinoids are available for prescription and non-prescription use, research is needed to determine how to use them safely and effectively."

Gene Morse, SUNY Distinguished Professor

School of Pharmacy and Pharmaceutical Sciences

Buffalo, N.Y. — The University at Buffalo’s Center for Integrated Global Biomedical Sciences (CIGBS) is partnering with Pure Jamaican/Seven-10 Pharmaceuticals and DENT Neurologic Institute in Western New York to research safe and therapeutic uses of cannabinoids — the substances found in the cannabis plant, such as tetrahydrocannabinol (THC) and cannabidiol (CBD).

This new scientific initiative creates a hub of pharmaceutical research in Kingston and Montego Bay, Jamaica, and builds on the established global cannabinoids research program led by Gene Morse , PharmD, director of the CIGBS, co-director of the SUNY Global Health Institute, and SUNY Distinguished Professor in the School of Pharmacy and Pharmaceutical Sciences.

The work will include Buffalo-based pharmacology laboratory research and clinical trial design, study guidance and enrollment, depending on the stage of drug development, in the United States, Jamaica and Brazil.

“Cannabinoid research requires a consistent drug product, and it’s mandatory for research integrity,” Morse said. “This collaboration establishes a framework for creating multinational clinical trials paired with a consistent supply of novel pharmaceutical-grade botanical medicines produced in a GMP (good manufacturing practices)-certified facility in Jamaica.”When a facility is GMP-compliant, its manufacturing processes are clearly defined, controlled, and validated to produce consistent, high-quality products.The CIGBS, which includes UB researchers in pharmacy, dentistry, public health, chemistry, informatics and medicine, will create drug assays that can measure cannabinoids and how they are metabolized in both animals and humans. Blood samples from these animal and human studies help the researchers understand how the cannabinoids are absorbed, distributed and eliminated. This data is then used to determine the proper therapeutic dosing regimens.“Although cannabinoids are available for prescription and non-prescription use, research is needed to determine how to use them safely and effectively,” Morse said. “Clinical research is ongoing in the management of chronic non-cancer pain, opioid use […]

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