[Imagen 3] Follow PsyPost on Google News A new study published in the Journal of Psychopharmacology suggests that intravenous ketamine, when administered in a setting that mirrors psychedelic-assisted therapy, can lead to substantial and sustained reductions in symptoms of post-traumatic stress disorder (PTSD). Researchers analyzed records from 117 patients with treatment-resistant PTSD and found that the majority experienced meaningful improvement, with over 60% reaching remission. The findings highlight the potential of ketamine in therapeutic environments that emphasize preparation, integration, and sensory immersion.
PTSD is a mental health condition that can develop after a person experiences or witnesses a traumatic event. People with PTSD often suffer from intrusive memories, flashbacks, avoidance of reminders, negative shifts in mood and thinking, and heightened states of anxiety or arousal. The disorder affects millions worldwide and is particularly prevalent among military veterans, first responders, and survivors of violence or disaster.
Traditional PTSD treatments include therapy and medications, but these options are not always effective. Talk therapies such as cognitive-behavioral therapy can take time and may not work for everyone. Medications, particularly antidepressants, help some patients but can have side effects and take weeks to show results. Many individuals with PTSD struggle with treatment resistance, meaning that conventional approaches do not significantly alleviate their symptoms.
In recent years, researchers have explored alternative treatments that work more quickly and effectively for those who do not respond to traditional methods. Ketamine, originally used as an anesthetic, has gained attention for its fast-acting antidepressant effects and potential to treat other mental health conditions, including PTSD. Some studies have shown promising results, but others have been inconclusive. This inconsistency has led researchers to investigate whether the way ketamine is administered—particularly in settings that support psychedelic experiences—could influence its effectiveness.
To explore the effects of ketamine in a more supportive setting, researchers examined data from 117 patients receiving treatment at a New York City clinic specializing in psychedelic-assisted therapies. The clinic’s approach involved multiple components designed to enhance the therapeutic experience. Patients participated in preparatory discussions before ketamine infusions, which helped them set intentions for their treatment. During infusions, they wore eye masks and […]
Ketamine shows promise for treatment-resistant PTSD in psychedelic-style therapy settings
