Pterostilbene is a very potent antioxidant, stimulates Brain-Derived Neurotrophic Factor, promotes neuroplasticity, is anti-anxiety, boosts dopamine, and helps cognition, learning and memory Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene, PTE) is a naturally derived polyphenol antioxidant found in blueberries, grapes, and in the bark of the Indian Kino Tree.
Pterostilbene, a naturally occurring dimethylether analog of resveratrol , is a phytoalexin that, like resveratrol, is made by plants to fight infection, insect infestation, heat and ultraviolet exposure. [i] Pterostilbene from blueberries Pterostilbene and resveratrol are both ‘stilbene’ polyphenols. But Pterostilbene is much more bioavailable than resveratrol. It rapidly crosses the blood-brain barrier , and stays in your body much longer than resveratrol (half-life of 105 mins. vs. 12 mins.). [ii]
Pterostilbene shows 80% bioavailability while resveratrol only has 20% bioavailability. [iii]
Pterostilbene is gaining a reputation in the nootropics community for controlling brain inflammation , boosting dopamine , helping reverse cognitive decline and fighting brain cell aging .
Pterostilbene helps: Neuroplasticity . Pterostilbene increases hippocampus neurogenesis , boosts insulin-like growth factor-1 (IGF-1) , and modulates the receptor kinase pathway that is central in the learning and memory process. Increasing neuroplasticity in the hippocampus improves learning and memory functions. [iv]
Neuroprotectant . Pterostilbene is a potent antioxidant and anti-inflammatory. It reduces reactive oxygen species (ROS) , and increases the antioxidant glutathione and superoxide dismutase (SOD) . [v] Crucial to overall brain health, maintaining signaling pathways and leading to improved learning and memory.
Brain-Derived Neurotrophic Factor (BDNF) . Pterostilbene has been shown in clinical trials to elevate BDNF in the hippocampus. Improving learning and memory. [vi]
What is Pterostilbene?
Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene, or PTE) is a naturally-derived polyphenol antioxidant primarily found in blueberries and the Indian Kino Tree. Pterostilbene Pterostilbene and resveratrol are both ‘stilbene’ polyphenols. And both boost cognition , learning and memory . But Pterostilbene works differently than Resveratrol. And is not a replacement for Resveratrol.Here’s why…Resveratrol has been getting a lot of press lately because of its ability to boost learning, memory and cognitive power. But Pterostilbene is much more bioavailable than resveratrol. And may be the preferred polyphenol to add to your […]

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